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RG 14620

CAS No. 136831-49-7

RG 14620 ( RG 14620; TYRPHOSTIN RG 14620. )

产品货号. M17976 CAS No. 136831-49-7

RG14620 is an epidermal growth factor receptor (EGFR) inhibitor.

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥243 有现货
5MG ¥389 有现货
10MG ¥567 有现货
25MG ¥1126 有现货
50MG ¥2203 有现货
100MG ¥3686 有现货
500MG ¥7995 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    RG 14620
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    RG14620 is an epidermal growth factor receptor (EGFR) inhibitor.
  • 产品描述
    RG-14620 is an EGFR inhibitor. It is a non-phenolic tyrphostin analog, which is selective for the EGF receptor and long acting. It inhibits EGF-stimulated HER14 cell proliferation (IC50=3 μM) as well as tumor growth in vivo.
  • 同义词
    RG 14620; TYRPHOSTIN RG 14620.
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    HER14 colony formation; HER14 DNA synthesis
  • 研究领域
    Cancer
  • 适应症
    ——

化学信息

  • CAS Number
    136831-49-7
  • 分子量
    275.13
  • 分子式
    C14H8Cl2N2
  • 纯度
    98%
  • 溶解度
    DMSO : ≥ 26 mg/mL; 94.50 mM
  • SMILES
    c1cc(cnc1)/C(=C\c1cc(cc(c1)Cl)Cl)/C#N
  • 化学全称
    (E)-3-(3,5-dichlorophenyl)-2-(pyridin-3-yl)acrylonitrile

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Yoneda T,et al. Cancer Res. 1991 Aug 15;51(16):4430-5.
产品手册
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